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Random thought: There isn't really a game that's tried to use the same "damage" mechanic as the Yoshi series, where the player is technically invincible to most forms of harm, but has a time limit to fulfill a "mission", for lack of term, before the player loses a life. No game that I can think of atm anyway.
Same goes for Sonic now that I think about it. It's kinda like Yoshi's Island (Or rather, Sonic did it somewhat first), just that the "mission" is easily completed for the first few times, and the life's not over if the "mission" is failed. Pretty genius game design imo, surpised that they haven't really been emulated much, if at all.